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The Cryobiology Process Explained

Cryosurgery is the application of extreme cold to cause cell necrosis. This is done by exploiting the thermodynamics effects of liquid gases.

Once a liquid gas is exposed or released it rapidly expands. Expansions requires energy which is derived from air or the surface with which it is in contact. Skin is thermo-conductive. Therefore by delivering the cryogen efficiently to and limiting contact with the skin using the Cryofunnel delivery system, we can maximise the effectiveness of a freeze cycle.

 

 

 

Stage 1 The cell at normal body temperature. The cell is at it's normal size, the cell membrane is elastic and the content is over 90% water

 

 

 

Stage 2 The cell during the freezing stage. The water expands and stretches the cell membrane causing minor or major damage.

 

 

 

Stage 3. The cell during the thawing stage. As the water thaws it contracts into a liquid form again. However, some of the water molecules form into crystals. This raises the osmotic potential within the cell and even more water enters the cell.

 

 

 

Stage 4. The cell during a repeated freezing stage. Water within the cell expands and stretches an already damaged cell, resulting in further damaged and ultimate rupture and death of the cell.

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